Our customers include:
Note: customer logos are registered trademarks for their respective organizations and do not constitute and endorsement.
Resonant Acoustic Mixing (RAM) technology is highly valuable in the pharmaceutical mixing industry due to its ability to mix powders, liquids, and semi-solids efficiently, precisely, and gently—without the drawbacks of traditional mixing methods. Here's a breakdown of why RAM is particularly useful in pharmaceutical applications:
- Quality at speed — fast processing with superior homogeneity
- Gentle processing — low shear, low heat
- Multifunctional technology — mixing, dry powder coating, milling, granulation, chemical reaction
- Bladeless — no blades or impellers, no cross-contamination
- Low waste — easy to clean, less to throw away, environmentally friendly
- Seamless scaleup — consistent results and recipes from lab to production
Pharmaceutical Mixer Testimonials
“…[We had] challenges with mixing a viscous (~10,000cp) solids-loaded cream consisting of water, excipient, API, and a sticky acrylate adhesive. It used to take multiple material addition steps and up to 8 hours with an overhead stirrer to achieve desired uniformity. With a LabRAM we performed the mix in a little more than 2 min…”
- U.S. biopharmaceuticals company
“...having these LabRAM II units has changed our processes in a positive manner. Every process involved with these units has become more stream-lined, and yield better and more consistent results.”
- Global pharmaceutical company
“We use these LabRAMs day in and day out, 18-20 hours a day…we run the heck out of them. We’re mixing several different powders in different quantities and no liquids. These [LabRAM] mixers do the trick.”
- U.S.-based neutraceuticals company
500+ Independent Research Articles Prove RAM is Superior
Pharmaceutical Research Featuring ResonantAcoustic® Mixers
Videos on Pharmaceutical Mixing
Resonant Acoustic Applications in the Pharmaceutical Industry
RAM is capable of much more than just mixing. ResonantAcoustic® technology is ideal for advanced material processing including pharmaceutical mixing, milling, coating, and chemical reaction. Here is a list of common use-cases where RAM shines above the rest:
Mixing Applications
- API and Excipient Powders
- Viscous gels
- HTE/HTS
- Liquid suspensions
- Pharmaceutical compounding
Milling Applications
- Nano milling
- Ball/bead milling
- Grinding
- Deagglomeration
- Solubility/Bioavailability
Coating Applications
- Dry powder coating
- Wet coating
- Delayed release
- Taste masking
- Coating preparation
Reaction Applications
- Green chemistry
- Solvent reduction
- Cocrystal formation
- Mechanochemistry
RAM Compliance in the Pharmaceutical Industry
RAM is fully compliant with pharmaceutical standards, including cGMP, IQ/OQ/PQ, and FDA 21 CFR Part 11. Discuss your compliance needs with a sales engineer to understand the required specification to meet your needs.
RAM CASE STUDIES IN PHARMACEUTICAL APPLICATIONS
How RAM Has Transformed Operations in Pharma Processing
VALIDATING RAM FOR PHARAMACEUTICAL MIXING AND PROCESSING
Pharmaceutical mixing eqiupment is critical. RAM is available for testing and validation through the following process:
- Demonstration
A sales engineer will arrange an online demonstration via conference call to show you a lab scale version or
RAM so you can see for yourself how it works. In some locations, we can offer in-person visits. - Free material testing
We can arrange a free mix, coating, milling, or reaction test with your material or a suitable surrogate. You
send us the material, we process it, document it, and send it back to you for validation. Material SDS required,
no hazardous materials accepted. - Rental program
We offer the LabRAM I for a monthly rental, with the first month’s rent applying to the cost of a purchase. Try
RAM out in your lab and run as many tests as you would like. - Quotation
Once you have had time to evaluate RAM through either a demonstration, mix test, or rental, we will provide a
quote that matches your application needs, however simple or complex they may be. - Performance Testing
After purchase, we can also perform validation and testing (FAT, SAT, etc) of your new machine per your
requirements, including compliance, performance, quality, and safety tests prior to or post installation.
Patents Featuring RAM Technology
Many of our customers discover that RAM mixing, milling, coating, and chemical reaction technology is so powerful, they apply for US and International patents to protect their process design and newfound competitive edge.
Key examples include:
